New research has found that the use of antidepressants increased the odds of implant failure by four times. Each year of antidepressant use doubled the odds of failure. While these drugs are often used to manage mood and emotions, a side effect decreases the regulation of bone metabolism, which is crucial to the healing process. For an implant to heal properly, new bone must form around it to secure it in place.
While antidepressant medication can relieve depression symptoms, their benefits must be weighed with the side effects. Four of the many known side effects that are reported in the literature are a big concern to dentists in regard to oral and bone health. These side effects of the drug include osteoporosis, a condition in which bones become weak and brittle; akathisia, a disorder characterized by the need to be in constant motion, including the head and jaw; bruxism, or teeth grinding; and dryness of the mouth, all of which affect the implant healing process.
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